Women’s History Month: A focus on women’s health 
 Postpartum depression is more  
 common than you might think 
 New mothers may experience  
 a range of emotions  
 shortly after giving birth -  
 from overwhelming joy to  
 extreme sadness.  
 Emotions can affect anyone during pregnancy  
 and after giving birth, and just like  
 the onset of emotions do not discriminate,  
 neither does postpartum depression (PPD),  
 which can affect any woman, regardless of  
 her age, ethnicity, marital status or income.  
 PPD is one of the most common medical  
 complications of pregnancy or childbirth.  
 Approximately 1 in 8 mothers in the  
 U.S. report experiencing symptoms of  
 PPD each year, equating to over 500,000  
 women. While it is common for new  
 mothers to experience a wide range of  
 emotions shortly after giving birth, persistent  
 sad, anxious or “empty” mood, irritability, 
  and feelings of guilt, worthlessness, 
  hopelessness or helplessness could be  
 symptoms of PPD.  
 The exact cause of PPD is unknown.  
 Hormonal changes that occur during and  
 after pregnancy and life stress can contribute  
 to PPD. Women with a history of  
 depression have an increased risk of developing  
 PPD. 
 Recognizing PPD can be challenging as  
 some new moms may think they have the  
 “baby blues,” which are often characterized  
 by mild symptoms including mood changes, 
  feelings of worry, tearfulness, irritability  
 and sleep difficulties that typically last for a  
 few days or one to two weeks, and do not  
 impact a mother’s ability to care for herself  
 or her family. While PPD persists often  
 with more severe symptoms, it can impact  
 not only the mother but can often extend to  
 children and a partner.  
 Signs and symptoms  
 of PPD include: 
 •  persistent sad mood 
 •  loss of interest or pleasure in hobbies  
 and activities 
 • difficulty sleeping 
 • abnormal appetite 
 • weight changes 
 • irritability 
 •  feelings of guilt or worthlessness 
 •  difficulty concentrating, remembering  
 or making decisions 
 •  aches or pains without clear physical  
 cause 
 •  trouble bonding with the new baby 
 •  persistent doubts about the ability to  
 care for the baby 
 •  thoughts about death, suicide or harming  
 oneself or the baby 
 If you know a mom who seems to be struggling  
 during pregnancy or after childbirth, do  
 not ignore it and hope their symptoms subside; 
  help them get in touch with a doctor  
 right away - she could have PPD, a medical  
 condition that if left untreated, can have serious  
 health effects on both the mom and baby. 
 Despite its prevalence, it is estimated that  
 approximately 50% of PPD cases may go  
 undiagnosed. This may be due to a lack of  
 awareness of the warning signs, ability to  
 differentiate between PPD and the “baby  
 blues” or because some mothers are embarrassed  
 and do not seek treatment for fear  
 of being judged by their family or friends. 
 With limited pharmaceutical options  
 available for postpartum depression,  
 new treatments are currently being studied. 
  The SKYLARK study, initiated by Sage  
 Therapeutics Inc., is evaluating the efficacy  
 and safety of an investigational oral medication  
 in women with severe PPD. An investigational  
 medication is a medication that is being  
 tested to determine if it is safe and effective for  
 a specific condition or group of people. 
 The SKYLARK study is seeking moms  
 experiencing symptoms of PPD for participation  
 in the clinical trial. New mothers  
 who are interested and eligible to participate  
 will receive close monitoring of their  
 postpartum depression symptoms by qualified  
 study nurses and clinicians, under the  
 guidance of the study doctor. Participants  
 will also receive study-related medical care  
 and the assigned investigational oral medication  
 at no cost. 
 To learn more about postpartum depression, 
  read about the SKYLARK study, or  
 take a screening questionnaire, please visit  
 www.skylarkppdstudy.com. 
 — Courtesy of BPT 
 20     March 10, 2022 Schneps Media 
 
				
/www.skylarkppdstudy.com
		/www.skylarkppdstudy.com